Duke Nukem 3D is a first-person shooter video game developed by 3D Realms. It is a sequel to the platform games Duke Nukem and Duke Nukem II, published by 3D Realms.

Duke Nukem 3D features the adventures of the titular Duke Nukem, voiced by Jon St. John, who fights against an alien invasion on Earth. Along with Wolfenstein 3D and Doom, Duke Nukem 3D is considered to be responsible for popularizing first-person shooters, and was released to major acclaim.